• KombatWombat@lemmy.world
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    6 days ago

    Genetics are a factor, but outside of extreme cases they are going to play a small role. Obesity is a modern epidemic, and we didn’t all suddenly mutate. Environmental factors are much more impactful.

    • tankplanker@lemmy.world
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      6 days ago

      The last time I saw this come up there were approx. 500 calorie difference between the top and the bottom for similar fitness/build of the genetics curve.

      500 calories is a pretty big workout, but its at the opposite ends of the curve, most people will be around 250 calories of the middle.

      What is far more important is the genetic and learned response to feeling full and hunger. Saying its easy for people to just switch track on that is frankly an awful take, the current weight loss drugs work for a reason, while you carry on taking them. People rebound from often impressive weight loss in huge numbers for a reason, and its not because they forget how to calorie count or exercise.

      • lightnsfw@reddthat.com
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        6 days ago

        Yeah a couple friends of mine REALLY struggled to lose weight until they got on one of those ozembic drugs. They’d doet for a while but it got to the point where they literally couldn’t stop thinking about food and they’d fall off the wagon. Whatever they’re taking kills those food cravings and they’re both at good weight now.

      • KombatWombat@lemmy.world
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        5 days ago

        500 calories is a pretty big workout, but its at the opposite ends of the curve, most people will be around 250 calories of the middle.

        Most people will be around 250 calories of the middle? What do you mean by this? You are talking about a difference between caloric intake between multiple people right?

        Saying its easy for people to just switch track on that is frankly an awful take, the current weight loss drugs work for a reason, while you carry on taking them.

        Did you reply to the right comment? I never said anything like this.

        • tankplanker@lemmy.world
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          5 days ago

          Multiple people of similar height, weight, fitness levels yes. There can be a measurable difference and it can easily be as much as a medium to heavy workout, for the average to extreme ends of the scale.

          Obviously someone who eats heathly, has a high percentage of muscle, exercises multiple times a week, will clearly burn even more calories than the same person who does none of that. What I am referring to is people who are close enough in these attributes and there still is a significant genetic difference.

          This is very much genetics having an impact. It doesnt even cover the genetic difference between hunger sensitivity issues for things like insulin or GLP-1, which can massively impact dieting success.

          I am not saying that environmental factors such as a life long poor diet and lack of exercise dont make this worse on top, but that genetics is a significant factor.

          Second part is piggy backing, so apologies if it appears aimed at you.

    • exasperation@lemmy.dbzer0.com
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      6 days ago

      Obesity is a modern epidemic, and we didn’t all suddenly mutate. Environmental factors are much more impactful.

      But not everyone got equally obese, even in the same environments, during these time periods. What portion of the population was predisposed to extra large impacts of unhealthy foods, sedentary lifestyles, external stressors, etc., when those environmental factors weren’t as prevalent?

      So for completeness, it’s a bunch of feedback loops between genetic factors, epigenetic factors, and environmental factors, including cultural/social factors. Some genetic factors make it harder or easier in the environments we live in (and some environments make it harder or easier).